Application

Naila from Germany applies for Blue Card United Kingdom

Biologists, botanists, zoologists and related professionals

Personal data:

For personal data please contact us
with the following Applicants-ID: 11581

Profession:

Name of profession: Biologists, botanists, zoologists and related professionals Name of latest business sector: University Hospital Goettingen Latest occupation/title: Post Doctoral Researcher Latest main activities: Biomedical Scientist

Education:

Completed education: doctoral Title or Qualification: PhD Specialisation: Gastroenterlogy and Endocrinology Additional trainings: Animal Husbandary

Preferred countries:

1. Preferred country | region / city: United Kingdom | Edinbrugh 2. Preferred country | region / city: Germany | Goettingen 3. Preferred country | region / city: France | Paris

Language skills:

1. Language skills: english => excellent 2. Language skills: 3. Language skills: =>

Personal note /detailed application:

RESEARCH EXPERIENCE
2012 to current Post-doctoral Researcher at University Hospital of Goettingen, Department of Gastroenterology and Endocrinology (in combination with radiation oncology), Germany.
Projects:
• Comparison of expression pattern and localization of iron metabolism proteins in rat hepatic and extra-hepatic organs during acute inflammation: in-vivo and in-vitro studies.
• Changes in gene expression, iron uptake and localization pattern of iron related proteins in radiation induced liver damage.
• Changes in gene expression of iron metabolism proteins in drug induced acute and chronic rat liver damage.
• Investigation of different transcriptional factors in regulation of iron metabolism genes
2009-11 PhD at University Hospital of Goettingen, Dept. of Gastroenterology and Endocrinology. Germany.
Project: Comparison of expression pattern and localization of iron metabolism proteins in rat hepatic and extra-hepatic organs during acute inflammation: in-vivo and in-vitro studies.
2007-08 BSc (Hons.) Research Project at University of Punjab, Dept. of Zoology. Pakistan.
Project: “Hematological and Serum Protein Study in Steel Furnace Workers”
2008-09 Biological Research Project at University Hospital of Goettingen, Dept. of Gastroenterology and Endocrinology. Germany.
Project: Expression of Prospero-related Home box 1 (prox1) Transcription factor and Epithelial Adhesion Molecule (EpCAM) in a rat model of Intrahepatic Cholangiocarcinogenesis.”

EDUCATION
2009-11 PhD in Molecular Biology University Hospital Goettingen, Dept. of Gastroenterology and Endocrinology. Grade: Magna Cumlaude.
2004-08 BSc (Hons.) in Zoology University of Punjab, Dept. of Zoology. First Division, 5th Position
2002-04 FSc (Pre-Medical) Kinnaird College University for Women. Lahore, Pakistan. First Division
2000-02 Matriculation Farooqi Girls High School. Lahore, Pakistan. First Division.


TRANSFERABLE SKILLS
Organization and time management skills: Inducted four new students and two technicians into the lab simultaneously, organizing, equipment and starting materials for projects.
Communication Skills: Well developed presentation skills, giving regular internal seminars. Excellent written communication skills, with three first author and seven co-author publications in different journals.
Team skill: Dedicated team player and collaborative worker in the research groups.
People Management: Oversaw specific needs of the inducted students and technicians in our research group.
Information Technology: Experienced user for Reference Manager, Microsoft, adobe photo shop, Prism, Image J, Axiovision, RT-PCR, bioinformatics tools.
Technical Expertise: Development of animal (rat and mice) experimental models, RNA and protein isolation and purification, RT-PCR, one and two dimensional gel electrophoresis, Western blot, immunohistochemistry, immunoprecipitation, Transfection, hepatic cell isolation and stimulation, human cell line culture and stimulation), primer designing, troubleshooting strategies.

PUBLICATIONS

1. Naz N. Moriconi F., Ahmad S., Amanzada A., Mihm S., Ramadori G., Malik I.A. Ferritin L is the sole serum ferritin constituent and a positive hepatic acute phase protein. SHOCK., 2013. In press.

2. Ahmad S.*, Moriconi F.*, Naz N., Sultan S., Sheikh N., Ramadori G., Malik I.A. Ferritin L and ferritin H are differentially located within hepatic and extra hepatic organs under physiological and acute phase conditions. Int J Clin Exp Pathol 2013;6(4):622-629.
* Equal authorship

3. Fränk M. R., Malik I.A., Christiansen H., Naz N., Sultan S., Amanzada A., Blaschke M., Cameron S., AhmadS., Hess C. F., Ramadori G., Moricon F. Rat model of fractionated (2Gy/day) 60 Gy irradiation of the liver: long-term effects. Radiation and Environmental Biophysics. 2013. Under revision.
4. Shakil Ahmad, Sadaf Sultan, Naz N. Ghayyor Ahmad, Salamah Alwahsh, Silke Cameron, Federico Moriconi, Guiliano Ramadori, and Ihtzaz Malik. Regulation of iron uptake in primary culture rat hepatocytes: The role of acute phase cytokines. AJP: 2013 (under rvision).

5. Naz N., Malik I., Sheikh N., Ahmad S, Khan S., Ramadori G., Ferroporti-1 is a negative acute phase protein in rat hepatocytes. A comparison with other iron transporters. Lab. Invest. 2012.

6. Malik, I.A*, Naz N.*, Sheikh, N., Khan S., Moriconi, F., Blaschke M. Comparison of changes in gene expression of transferrin receptor-1 and other iron-regulatory proteins in rat liver and brain during acute-phase response. Cell Tissue Res. 2011 May; 344(2):299-312.
* Equal authorship

7. Ahmad A., Malik I.A., Nischwitz M., Sultan S., Naz N., Ramadori G. Myeloperoxidase and elastase are only expressed by neutrophils in normal and in inflammed liver. Histochem Cell Biol. 2011 Mar; 135(3):305-15.

8. Sheikh N., Naz N., Qureshi A.W. Impact of work place environment on the hematology and serology of steel industry workers. Health MED, 2011 5(1)35-40.

9. Sheikh N., Masood M., Naz N. Hematological and serological changes in the pre- and post-treatment breast cancer patients. Health MED. 2011. In press.

10. Wójcik M, Ramadori P, Blaschke M, Sultan S, Khan S, Malik IA, Naz N, Martius G, Ramadori G, Schultze FC. Expression of cyclooxygenase-2 (COX-2) is restricted to “resident” tissue macrophages in rat liver injury and cholangiocarcinoma development. Histochem Cell Biol. 2011 Dec 1.

11. Malik, I.A., Baumgartner BG., Naz N., Sheikh, N., Moriconi, F., Ramadori G. Changes in gene expression of DOR and other thyroid hormone receptors in rat liver during acute-phase response. Cell Tissue Res. 2010 Nov; 342(2):261-72.

12. Malik, I.A., Moriconi, F., Sheikh, N. Naz N. Dudas, J. Mansuroglu, T., Hess, C.F., Rave-Fränk MChristiansen, H., Giuliano Ramadori. Single-dose gamma-irradiation induces up-regulation of chemokine- gene expression and recruitment of granulocytes into the portal area but not into other region of rat hepatic tissue. Am J Pathol. 2010 Apr; 176(4):1801-15.

13. Sheikh N., Manzoor F., Ahmed R., Naz N. and. Malik S.A. Laboratory study of repellency and toxicity of Tenekil, Termidor and Terminus against subterranean termite Heterotermes indicola (Wasmann) in Pakistan. Sociobiology 2008 51(3) 749-764.

PUBLISHED ABSTRACTS

1. Ferroporti-1 is a negative acute phase protein in rat hepatocytes. A comparison with other iron transporters. EASL 2013. Amsterdam, The Nederlands.

2. Ferritin L and ferritin H are differentially located within hepatic and extra hepatic organs under physiological and acute phase conditions. APASAL 2013. Singapore.

3. EPO gene expression and regulation in rat liver after X irradiation. APASAL 2013. Singapore

4. Differential localization of iron transport proteins in rat liver and spleen during acute phase response. 27th Annual 29. Jahrestagung der GASL, 2013 Germany.

5. Nuclear localization of iron transport proteins in rat liver and spleen indicates nuclear iron sequestration during acute phase response. FALK. 2013. Germany.
6. Changes in EPCAM and Prox-1 expression in a rat model of Cholangiocarcinogenesis in 26th Annual 28. Jahrestagung der GASL, 2012 Germany.
7. Ferroportin-1 behaves as a negative acute phase protein in liver. 6th Fall Meeting of the DGAV together with the Associations 2012. Germany. (DGAV-Prize winning work)
8. FTL is the sole serum ferritin and a positive secretory acute phase protein. World Congress on Cell Science & Stem Cell Research. 2012 USA.
9. Lipocalin-2 role in transferrin receptor1 dependent and independent iron uptake in cultured rat primary hepatocytes. World Congress on Cell Science & Stem Cell Research. 2012 USA.
10. Expressional changes of DOR and other thyroid hormone effector genes in rat liver during acute-phase response in 26th Annual 27. Jahrestagung der GASL 2011 Germany
11. Myeloperoxidase and elastase are only expressed by neutrophils in normal and in inflamed liver in 27th Annual Jahrestagung der GASL 2011 Germany
12. Comparison of changes in the gene expression of transferrin receptor-1 and other iron regulatory proteins in the rat brain and liver during acute-phase-response. 100th Annual Meeting of United States and Canadian Society of Pathology (USCAP). Henry B. Gonzalez Convention Centre San Antonio, TX. 2011.
13. Haematological changes, serum iron and protein levels in the steel industry workers. in 9th Biennial Conference Advances in Biochemistry and Molecular Biology, 2009 Pakistan.


 

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